Im no expert, but looks like you are trying to run Po3 with 2GB Ram assigned. This is a very small amount and likely your issue. Try increasing to 3 or 4. (most run 5-6GB for Po3).
The error Pixel format not Accelerated is usually caused by outdated video card drivers. So, update all your drivers. However, it can also be caused by things like gamepads being connected. So if your drivers are up to date disconnect any extra peripherals you have and try again. Let us know if that helps. HanoverFist69
@Brainsnare Got any update for us? What Hanover and Deepcage both suggested should fix the issue for you